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chronaximetry是什么意思,chronaximetry翻译
Chronaximetry: A Powerful Tool in Electrophysiology
Chronaximetry is a technique used in electrophysiology to study the response of excitable cells, such as neurons and muscle cells, to electrical stimulation. It is based on the concept that the strength of a stimulate required to elicit a response in an excitable cell is directly related to the duration of the stimulus. This relationship between stimulus strength and duration is known as the chronaxie, which is the time required to double the amplitude of a response to a stimulus.
Chronaximetry has several advantages over other techniques used in electrophysiology. Firstly, it provides a sensitive measure of the membrane properties of excitable cells, such as the resting membrane potential,阈电位(threshold potential), and the membrane time constant. Secondly, it can be used to assess the integrity of excitable cell membranes, as alterations in membrane properties due to injury or disease can affect the chronaxie of the cell. Lastly, it can be used to study the effects of various compounds, such as drugs or toxins, on excitable cell function.
There are two main types of chronaximetry: constant current chronaximetry and constant voltage chronaximetry. In constant current chronaximetry, a constant current is applied to the excitable cell, and the duration of the stimulus is varied to determine the chronaxie. In constant voltage chronaximetry, a constant voltage is applied to the cell, and the amplitude of the stimulus is varied to determine the chronaxie.
One of the key findings in chronaximetry is the existence of the all